Widely praised by attendees,
the AGA has expanded to five
cities in 2016. There is no registration fee and all GI fellows
are encouraged to attend. For
further information, please visit www.gastro.org/psw, email
email@example.com, or contact
your program director. We look
forward to seeing you there! n
Houston, TX Baylor College of Medicine February 20, 2016
New York, NY Mount Sinai School of Medicine February 20, 2016
San Diego, CA University of California, San Diego February 20, 2016
Boston, MA Beth Israel Deaconess Medical Center March 18, 2016
Philadelphia, PA University of Pennsylvania April 6, 2016
ANSWERS // From page 3
Q1: ANSWER: B
All four factors may contribute to liver disease progression from chronic HBV infection,
but elevated hepatitis B DNA represents the
most important risk factor for histologic progression to cirrhosis and the development of
hepatocellular carcinoma. Large prospective
observational cohort studies have demonstrated significant differences in the risk for
HCC based on baseline HBV DNA levels in
patients observed for up to 13 years duration.
HBV genotype C has been associated with an
increased risk for severe liver disease and
HCC when compared with individuals with
genotype B infection. Elevated serum ALT is
associated with an increased risk of liver fibrosis progression and HCC risk. Tobacco use
is associated with increased HCC risk but does
not significantly impact liver fibrosis progression.
1. Chen C.J., et al. JAMA 2006;295:65-73.
2. Keeffe E. B., et al. Clin. Gastroenterol. Hepatol. 2006;4:936-62.
Q2: ANSWER: C
In the absence of alarm signs and symptoms, there is no evidence
to support the use of laboratory testing, x-rays, or endoscopy in the
routine management of constipated patients. However, there is good
evidence to support the use of physiological tests (e.g., manometry,
colon transit studies) to define the pathophysiologic features and to
Choice A: In the absence of alarm signs and symptoms, there is no evidence to support the use of laboratory testing, x-rays, or endoscopy in
the routine management of constipated patients.
Choice B: This patient has no other signs or symptoms of thyroid
disease. Therefore, repeat serologic testing would not be indicated.
Choice D: There is a very low likelihood that there is a structural colonic abnormality. Therefore, barium enema is not indicated.
Choice E: Computed tomography is not indicated as there is absence
of obstructive symptoms in the patient.
1. Brandt L.J., et al. Am J Gastroenterol. 2005:100:S5-21.
2. Longstreth G.F., et al. Gastroenterol. 2006:130:1480-91.